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Bioinformatics - Engineering

Bioinformatics is the application of statistics and computer science to the field of molecular biology. The term bioinformatics was coined by Paulien Hogeweg and Ben Hesper in 1978 for the study of informatics processes in biotic systems. Its primary use since at least the late 1980s has been in genomics and genetics, particularly in those areas of genomics involving large-scale DNA sequencing.

Bioinformatics now entails the creation and advancement of databases, algorithms, computational and statistical techniques and theory to solve formal and practical problems arising from the management and analysis of biological data.Common activities in bioinformatics include mapping and analyzing DNA and protein sequences, aligning different DNA and protein sequences to compare them and creating and viewing 3-D models of protein structures.

Major Research Areas:

  • Sequence Analysis
  • Genome Annotation
  • Computational Evolutionary Biology
  • Literature Analysis
  • Analysis of gene expression
  • Analysis of regulation
  • Analysis of protein expression
  • Analysis of mutations in cancer
  • Comparative Genomics
  • Modeling biological systems
  • High-throughput image analysis
  • Structural Bioinformatics Approaches
  • Prediction of protein structure
  • Molecular Interaction